The Metamorphoses of Ovid, Books VIII-XV

Under the consulate of Quintus Fabius Gurges, and Decimus Junius Brutus Scæva, Rome was ravaged by a frightful pestilence. The resources of physic having been exhausted, the Sibylline books were consulted to ascertain by what expedient the calamity might be put an end to, and they found that the plague would not cease till they had brought Æsculapius from Epidaurus to Rome. Being then engaged in war, they postponed their application to the Epidaurians for a year, at the end of which time they despatched an embassy to Epidaurus; on which a serpent was delivered to them, which the priests of the Deity xv. 745-762. assured them was the God himself. Taking it on board their ship, the delegates set sail. When near Antium, they were obliged to put in there by stress of weather, and the serpent, escaping from the ship, remained three days on shore; after which it came on board of its own accord, and they continued their voyage. On arriving at the Island of the Tiber the serpent escaped, and concealed itself amid the reeds; and as they, in their credulity, fancied that the God had chosen the place for his habitation, they built a temple there in his honour. From this period, which was about the year of Rome 462, the worship of Æsculapius was introduced in the city, and to him recourse was had in cases of disease, and especially in times of pestilence.